The ARCH Lab recently collaborated on a prospective study titled “Pre-Operative Predictors of Health-Related Quality of Life Two Years After Pediatric Epilepsy Surgery: A Prospective Cohort Study” involving 95 pediatric cases, aimed to uncover the pre-operative predictors of Health-Related Quality of Life (HRQOL) following epilepsy surgery. The HRQOL was assessed using the Quality of Life in Childhood Epilepsy Questionnaire (QOLCE)-55 both before surgery and two years later.
- QOLCE scores significantly improved after surgery
- Pre-operative predictors of enhanced HRQOL included:
- Using fewer anti-seizure medications
- An older age at seizure onset
- Higher pre-operative HRQOL
- Greater family resources and stronger family relationships
- Lower family demands
- Caregiver characteristics had no significant impact on post-operative HRQOL
- Multivariable regression analysis confirmed the importance of:
- Older age at seizure onset for improved HRQOL
- Higher pre-operative HRQOL for significantly better post-operative HRQOL
This study emphasizing the need to enhance pre-operative HRQOL for better post-surgery outcomes.